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- <text id=92TT2097>
- <title>
- Sep. 21, 1992: Transplant Trials
- </title>
- <history>
- TIME--The Weekly Newsmagazine--1992
- Sep. 21, 1992 Hollywood & Politics
- </history>
- <article>
- <source>Time Magazine</source>
- <hdr>
- THE WEEK
- HEALTH & SCIENCE, Page 18
- Transplant Trials
- </hdr><body>
- <p>The baboon liver did fine, it turns out. But the patient, now
- dead, had the AIDS virus
- </p>
- <p> For more than two months, the world's first baboon-to-human
- liver transplant patient seemed to be improving. Doctors
- successfully treated a mild case of tissue rejection a few weeks
- after the ground-breaking 11-hour operation at the University
- of Pittsburgh Medical Center. The problem did not recur, and by
- the end of July the new liver had tripled in size, matching a
- healthy human organ. But late last month a fever set in,
- followed by an infection--possibly caused by an injection of
- X ray-sensitive dye. The liver began to fail, and then, within
- a week, though the infection had started to subside, the man was
- dead of massive bleeding in the brain.
- </p>
- <p> The cause of the bleeding was not immediately known, but
- doctors said it was probably not due to rejection--which means
- the Pittsburgh team may try a similar transplant as early as
- the end of the year. The next time, the patient may be in
- better overall health: the hepatitis B that destroyed this man's
- own liver was just one of his medical problems.
- </p>
- <p> Perhaps the most serious--from an ethical, if not a
- medical, point of view--was that he was infected with HIV.
- Hospital spokesmen explained that policy forbids transplants for
- people with active AIDS but not for those who are merely
- infected, and that he fit the criteria. But critics charged that
- performing experimental surgery on someone who may have felt he
- had little choice was inappropriate.
- </p>
-
- </body></article>
- </text>
-
-